First COVID-19 autopsy “lungs stuffed with mucus”

Dr. Zhong Nanshan responded to the first COVID-19 patient autopsy on the 18th that the autopsy remains very important. “When SARS was done 17 years ago, the autopsy was used to understand the disease of the lungs and the damage to the organs outside the lungs.” According to Dr. Zhong, the lung performance of patients with new coronary pneumonia is a little different from that of the SARS case. “It’s not as severe fibrosis as we imagined. It seems that some alveoli are still there, but the inflammation is very strong. There is a lot of very viscous mucus, which led to the patient’s irregular lung ventilation. He said, “further anatomy will show that we recognize the characteristics of the disease, and at the same time, we need to pay special attention to keeping the airways of patients open. Related research is still in progress.”

Dr. Sun Yanrong, deputy director of the Biological Center of the Ministry of Science and Technology of China, said on the 17th that the antimalarial drug “chloroquine phosphate” has anti-neo coronavirus efficacy. In this regard, Dr. Zhong believes that chloroquine phosphate is effective for coronavirus. If it is really used in humans, it is in this epidemic. ”

According to the research conducted in both Guangdong and Beijing, a considerable number of patients could make the virus negative within 15 days. Even though it is unlikely to perform rigorous clinical trials, compared with other drugs, chloroquine phosphate made the fever and virus disappear about one day earlier. In addition, the side effects of chloroquine phosphate are not very large, even for patients with gastrointestinal symptoms such as diarrhea, tinnitus, etc. Judging by the existing signs, it should be helpful. ”

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